Subcutaneous Nodules of Rheumatoid Arthritis with Lipoid Deposition

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Subcutaneous Nodules of Rheumatoid Arthritis with Lipoid Deposition.

Weber and Freudenthal (1936-7), Weber (1943, 1944, 1947, 1948), and Fletcher (1946, 1947) have noted the rare occurrence of subcutaneous nodules in rheumatoid arthritis which consisted almost entirely of lipoid, and have designated such cases by various names to differentiate them from the " common " type of rheumatoid arthritis subcutaneous nodule. During the clinical examination of seventy ca...

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Necrobiotic nodules of rheumatoid arthritis type with lipoid deposition.

The incidence and structure of subcutaneous nodules in rheumatic fever and rheumatoid arthritis have been the subject of research for many years. In 1937 Collins published a paper on the subcutaneous nodule in rheumatoid arthritis, and in 1939 he reviewed in these Annals some of the work on the pathology of rheumatic fever and rheumatoid arthritis. He mentions the basic pattern of tissue change...

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Subcutaneous nodules in rheumatoid arthritis.

A 29 year old male with rheumatoid arthritis (RA) of 10 years duration presented with multiple subcutaneous nodules of one month duration while on methotrexate (7.5 mg once a week), salazopyrine (1000 mg/day) and methyl prednisolone (4 mg/day). The nodules involved tendons of metacarpophalangeal joints (Figure 1) and base of left great toe (Figure 2), were painless and did not interfere with hi...

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The significance of subcutaneous nodules in rheumatoid arthritis.

The presence of subcutaneous nodules in rheumatic fever is of serious prognostic significance because, as they are pathologically similar to the Aschoff bodies found in the heart, they generally indicate severe cardiac damage and active infection. As a rule nodules appear after the onset of the rheumatic heart lesion. There is, therefore, practically always cardiac involvement in cases where no...

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Subcutaneous Rheumatoid Nodules.

death to give reliable results. The postmortem interval as already defined established fixed limits for the interval and avoided possible overestimation of the amino acid concentration relative to time after death. Analysis of the results showed no evidence that a specific aminoacidopathy is implicated in the aetiology of cot death but has nevertheless improved our understanding of the biochemi...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 1949

ISSN: 0003-4967

DOI: 10.1136/ard.8.3.181